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A novel copper-containing protein from brain
M V Mikaelyan1, R M Nalbandyan
1Institute of Biochemistry, Academy of Sciences of Armenian SSR, Yerevan 375044, U.S.S.R.
Abstract:
A novel copper-containing protein has been isolated in electrophoretically homogeneous state from bovine brain extracts. Some physico-chemical properties of the protein are determined (molecular weight, copper content, isoelectric point, amino acid composition, optical and EPR spectra), and they are compared with those of neurocuprein, an extremely acidic copper protein isolated earlier from brain. A number of differences between neurocuprein and the novel protein are clearly shown, although certain similarities are also detected.
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