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Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
Muscles of the Eye01:20

Muscles of the Eye

The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and rotating...
Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
The Thyroid Gland01:23

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...

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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Radiologically manifested accessory extraocular muscles in thyroid eye disease.

Neil E Sinclair1, Michael A Roberts, Margaret D Hourihan

  • 1Cardiff Eye Unit, University Hospital of Wales, Cardiff, United Kingdom. sinclne@hotmail.com

Ophthalmic Plastic and Reconstructive Surgery
|May 27, 2010
PubMed
Summary
This summary is machine-generated.

Graves orbitopathy may involve previously unseen accessory orbital muscles. These muscles, typically hidden, become visible on imaging during this condition, offering new diagnostic insights.

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Area of Science:

  • Ophthalmology
  • Radiology
  • Anatomy

Background:

  • Graves orbitopathy is an autoimmune condition affecting the eye muscles.
  • Accessory extraocular muscles are rare anatomical variations.
  • Standard imaging techniques may not always visualize these structures.

Observation:

  • Three patients with Graves orbitopathy presented with unusual accessory orbital structures on CT and MRI scans.
  • These structures were isodense/isointense to the normal extraocular muscles.
  • The anatomical appearance resembled previously described accessory extraocular muscles.

Findings:

  • The study proposes that Graves orbitopathy activates or enlarges these accessory orbital muscles.
  • This involvement makes the accessory muscles detectable via orbital imaging.
  • The findings suggest a potential role for these structures in the pathophysiology of Graves orbitopathy.

Implications:

  • This observation could lead to improved diagnostic accuracy for Graves orbitopathy.
  • It may offer new targets for understanding and treating the condition.
  • Further research into accessory muscle involvement in Graves orbitopathy is warranted.