Ultra-wide-field imaging for cytomegalovirus retinitis.

Area of Science:

• Ophthalmology
• Medical Imaging

Background:

• Cytomegalovirus (CMV) retinitis is a serious ocular complication in patients with acquired immune deficiency syndrome (AIDS).
• Accurate imaging of the entire retina is crucial for assessing the extent of CMV retinitis and guiding treatment.

Purpose of the Study:

• To compare the diagnostic yield of the Optomap ultra-wide-field imaging system with conventional fundus photography in patients with CMV retinitis.
• To evaluate patient satisfaction with both imaging modalities.

Main Methods:

• Prospective study of patients with AIDS and CMV retinitis at Rush University.
• Simultaneous conventional nine-field fundus photography and Optomap ultra-wide-field imaging.
• Patient satisfaction questionnaire assessing comfort and imaging time.

Main Results:

• Optomap imaging captured 48.3% more retinal area and 40.0% more CMV retinitis area compared to standard photography.
• Conventional photography missed peripheral CMV lesions in two patients.
• Patients reported higher satisfaction with Optomap due to increased comfort and reduced imaging time.

Conclusions:

• Ultra-wide-field Optomap imaging provides a more comprehensive view of the retina, including peripheral CMV retinitis lesions.
• Optomap imaging offers a more comfortable and time-efficient experience for patients compared to conventional fundus photography.