Liquid-phase microextraction approaches combined with atomic detection: a critical review

Area of Science:

• Analytical Chemistry
• Separation Science

Background:

• Liquid-phase microextraction (LPME) offers advantages like preconcentration, simplicity, and cost-effectiveness.
• LPME integration with atomic detection techniques is an emerging area.
• Previous research has not fully explored the synergy between LPME and atomic detection.

Purpose of the Study:

• To provide a comprehensive review of liquid-phase microextraction (LPME) applications combined with atomic detection techniques.
• To discuss theoretical aspects, strategic combinations, and experimental parameters for LPME-atomic detection methods.
• To critically compare different LPME approaches for atomic detection.

Main Methods:

• Literature review of LPME applications with atomic detection.
• Analysis of theoretical principles and strategic integration of LPME with atomic techniques.
• Evaluation of experimental parameters impacting method development.

Main Results:

• LPME demonstrates significant potential for preconcentration and sample cleanup in atomic spectroscopy.
• Various LPME strategies can be effectively coupled with atomic detection methods.
• Key parameters influencing extraction efficiency and analytical performance were identified.

Conclusions:

• The combination of LPME with atomic detection techniques offers a promising avenue for sensitive and efficient elemental analysis.
• Further research and development in this area can lead to improved analytical methodologies.
• LPME-atomic detection provides a versatile platform with advantages in enrichment, efficiency, and operational simplicity.