Reformulation of a codeine phosphate liquid controlled-release product.

Eva Roblegg1, Peter Dittrich, Krista Haltmeyer

  • 1Department of Pharmaceutical Technology, Institute of Pharmaceutical Sciences, Karl-Franzens University of Graz, Graz, Austria. eva.roblegg@uni-graz.at

Summary

New ion-exchange resins offer a viable alternative for developing stable, controlled-release codeine formulations without Eudragit coating. These resins provide effective drug release and maintain stability for at least six months.

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