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Updated: Jun 12, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Pigmented poroid neoplasm mimicking nodular melanoma
Tsuyoshi Mitsuishi1, Shin-ichi Ansai, Takashi Ueno
1Department of Dermatology, Nippon Medical School, Bunkyou-ku, Tokyo, Japan.
Abstract:
We reported the case of a 92-year-old woman with a pigmented and non-pigmented surface of the pedunculated nodule on her lower leg. Microscopic examination revealed that this nodule consisted of a component of small, dark, homogenous, poroid cells and cuticular cells in the dermis. The histopathological features of the lesion were consistent with poroid neoplasm. Immunohistochemistry showed that HMB-45 and Melan-A were positive in malanocytes and melanophages of the pigmented areas. Unlike most poroid neoplasms, this case showed pigmented lesion mimicked nodular melanoma.
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