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Syntheses of trans-SCH-A and cis-SCH-A via a stereodivergent cyclopropanation protocol
Kristína Csatayová1, Stephen G Davies, James A Lee
1Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.
Abstract:
A highly diastereoselective cyclopropanation protocol has been employed in the syntheses of trans-SCH-A and cis-SCH-A. This strategy encompasses a stereodivergent procedure for the preparation of syn- and anti-cyclopropane diastereoisomers in high dr from a common allylic carbamate precursor.
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