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Holmium-161 produced using 11.6 MeV protons: A practical source of narrow-band X-rays
Bryan J Stephens1, Marcus H Mendenhall
1Department of Physics, Vanderbilt University, 6301 Stevenson Center, P.O. Box 351807 Station B, Nashville, TN 37235, USA.
Abstract:
We present a novel technique to produce narrow-band X-rays by preparing (161)Ho from the bombardment of dysprosium foil by 11.6 MeV protons. The activated foil produces predominantly 45-55 keV X-rays, which are suitable for activating iodinated radio-sensitizing agents (e.g. IUdR) for oncological therapy. We demonstrate that clinically useful quantities of the nuclide are easily produced with a medical cyclotron which is far from the current state of the art.
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