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Use of octreotide in the treatment of chylopericardium

Eszter Szabados1, Kalman Toth, Emese Mezosi

  • 1Division of Cardiology, First Department of Medicine, University of Pecs, Pecs, Hungary. eszter.szabados@aok.pte.hu

Heart & Lung : the Journal of Critical Care
|June 22, 2010
PubMed

Insights

Chylopericardium, a rare condition of chyle in the pericardium, was successfully treated with octreotide after standard therapies failed. This case highlights octreotide as a potential treatment for post-surgical chylopericardium.

Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Gastroenterology

Background:

  • Chylopericardium is pericardial effusion of chyle, often secondary to thoracic duct injury.
  • Coronary artery bypass grafting (CABG) can lead to thoracic duct injury and subsequent chylopericardium.

Observation:

  • A 46-year-old woman developed isolated chylopericardium post-CABG.
  • Initial conservative management (pericardial drainage, dietary modification) was unsuccessful.

Findings:

  • Subcutaneous octreotide administration (300 μg daily for 2 weeks) effectively reduced pericardial fluid production.
  • Pericardial fluid normalized by the end of octreotide treatment with no observed side effects.

Implications:

  • Octreotide offers a viable therapeutic option for refractory chylopericardium, particularly post-cardiac surgery.
  • This case expands treatment strategies for managing thoracic duct-related effusions.

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