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Related Experiment Video

Updated: Jun 12, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

Coil embolization training using a rabbit saccular aneurysm model.

T Tsumoto1, T Terada, H Yamaga

  • 1Department of Neurological Surgery, Wakayama Medical University, Japan.

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
|June 24, 2010
PubMed
Summary
This summary is machine-generated.

A novel rabbit aneurysm model was developed for coil embolization training. This effective model aids in learning endovascular coil embolization techniques and testing new embolic materials.

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Last Updated: Jun 12, 2026

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07:04

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Microsurgical Venous Pouch Arterial-Bifurcation Aneurysms in the Rabbit Model: Technical Aspects
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Published on: May 11, 2011

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit
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Published on: May 14, 2020

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Medical Device Development

Background:

  • Cerebral aneurysms pose significant clinical challenges.
  • Effective training models are crucial for mastering endovascular techniques.
  • Existing models may not fully replicate human aneurysm characteristics.

Purpose of the Study:

  • To develop and validate a rabbit saccular aneurysm model for coil embolization training.
  • To assess the feasibility of using this model for evaluating embolic materials.
  • To provide a reproducible platform for endovascular procedure simulation.

Main Methods:

  • Saccular aneurysms were induced in rabbits using elastase.
  • Aneurysm dimensions were monitored post-induction.
  • Electrically detachable (ED) platinum coils were used for embolization.
  • Post-embolization outcomes were evaluated.

Main Results:

  • Successful aneurysm induction in approximately 80% of rabbits.
  • Aneurysms exhibited broad necks and significant length.
  • Aneurysm size increased by approximately 1.5 times between postoperative days 14 and 28.
  • Complete embolization was achieved in all cases using 18-sized ED platinum coils.
  • A neck remnant was observed in most post-embolization aneurysms.

Conclusions:

  • The developed rabbit aneurysm model is suitable for coil embolization training.
  • This model serves as a valuable tool for testing novel embolic materials.
  • The rabbit model offers an effective training modality for endovascular coil embolization procedures.