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Updated: Jun 11, 2026

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
Published on: June 3, 2019
[Functional characteristics of cardiovascular system in adolescents with prehypertension]
Abstract:
Based on the results of sanogenetic monitoring the health of schoolchildren found that among high school students to the proportion of adolescents with elevated blood pressure (hypertension + hypernormotension) increases from 15-20% in 8th class to 30-50% in 9-11th classes, while the proportion of adolescents with hypertension was 3.7% in all age groups. Comparison of blood pressure with parameters of neurovegetative regulation of the cardiovascular system revealed that the presence of high normal blood pressure in 13-14-year-olds and 17-18-year-olds correlated with an increase in the proportion of low frequencies in the spectrum of HRV and lower values of the sensitivity of arterial baroreflex. At the age of 15-16 years, high-normal blood pressure accompanied by a decrease in heart rate, increase the sensitivity of arterial baroreflex and correlates with reduced power high-frequency part of the spectrum of HRV. When performing a functional test (an increase of "dead" breathing space) in hypernormotension teenagers 15-16 years, unlike normotensive peers, there is a reduction of finger blood pressure, and relative power of low frequencies in the spectrum of HRV, which may be associated with maladaptive functional changes in the sympathetic unit of autonomic regulation.
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