Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A unimolecular GLP-1 and FGF21 dual agonist for treatment of metabolic dysfunction-associated steatohepatitis.

Communications medicine·2026
Same author

The Polymers of Life: Exploring Cellular Function Through Polymer Concepts.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Soaking Up Success: Sponge-Assisted Nanoparticle Transfection.

Research square·2026
Same author

Genetically Encoded Sterol-Modification of a Synthetic Intrinsically Disordered Protein Drives Its Self-Assembly Into Diverse Morphologies.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

All-PEG-Like Block Copolymers Self-Assemble into Stealth Nanocarriers for Drug Delivery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Intrinsically Disordered Protein Coating for Oral Delivery of Peptide Drugs.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Jun 11, 2026

Design and Development of a Three-Dimensionally Printed Microscope Mask Alignment Adapter for the Fabrication of Multilayer Microfluidic Devices
06:21

Design and Development of a Three-Dimensionally Printed Microscope Mask Alignment Adapter for the Fabrication of Multilayer Microfluidic Devices

Published on: January 25, 2021

A versatile diffractive maskless lithography for single-shot and serial microfabrication.

Nathan J Jenness1, Ryan T Hill, Angus Hucknall

  • 11Center for Biologically Inspired Materials and Material Systems, Duke University, Durham, NC 27708, USA. njenness@seas.rochester.edu

Optics Express
|July 1, 2010
PubMed
Summary
This summary is machine-generated.

This study presents a rapid diffractive maskless lithography system for creating 2D and 3D micropatterns. The adaptable technology fabricates microstructures in photoresist and active protein microstructures with high resolution.

More Related Videos

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture
09:51

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture

Published on: June 16, 2016

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Related Experiment Videos

Last Updated: Jun 11, 2026

Design and Development of a Three-Dimensionally Printed Microscope Mask Alignment Adapter for the Fabrication of Multilayer Microfluidic Devices
06:21

Design and Development of a Three-Dimensionally Printed Microscope Mask Alignment Adapter for the Fabrication of Multilayer Microfluidic Devices

Published on: January 25, 2021

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture
09:51

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture

Published on: June 16, 2016

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Area of Science:

  • Optics and Photonics
  • Materials Science
  • Biotechnology

Background:

  • Micropatterning is crucial for microfabrication across various scientific disciplines.
  • Existing lithographic techniques often face limitations in speed, flexibility, or resolution.

Purpose of the Study:

  • To demonstrate a novel diffractive maskless lithography system.
  • To enable rapid, arbitrary, and high-resolution micropatterning in both serial and single-shot modes.
  • To fabricate both microstructures in photoresist and functional protein microstructures.

Main Methods:

  • Utilizing phase holograms on a spatial light modulator to create arbitrary light intensity distributions.
  • Employing diffractive optics for maskless patterning.
  • Developing a graphical user interface for simplified operation and mode switching.

Main Results:

  • Achieved rapid serial and single-shot micropatterning capabilities.
  • Demonstrated the formation of 2D and 3D micropatterns/structures in diverse substrates.
  • Attained a minimum resolution of approximately 700 nm, outperforming theoretical limits in certain aspects.
  • Successfully fabricated functional protein microstructures, preserving biological activity.

Conclusions:

  • The developed diffractive maskless lithography system offers a rapid, adaptable, and versatile solution for microfabrication.
  • The technology enables parallel fabrication of microstructures with high precision.
  • This method holds potential for applications in microelectronics, photonics, and biomedical engineering.