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Updated: Jun 11, 2026
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Macroglobulinosis cutis revealing Waldenström macroglobulinemia]
E Rivière1, C B Ghiringhelli, I Peyrot
1Inserm U897, service de médecine interne et tropicale, hôpital Saint-André, CHU de Bordeaux, université Bordeaux 2 Victor-Segalen, 1, rue Jean-Burguet, 33000 Bordeaux, France. e.riviere@neuf.fr
Abstract:
Waldenström macroglobulinemia is defined by a bone marrow lymphoplasmacytic infiltration associated with serum IgM monoclonal gammopathy. Specific properties of the IgM gammopathy induce the main clinical manifestations revealing the disease: hyperviscosity syndrome, autoimmune peripheral neuropathy, cryoglobulinemia or hemolysis, and exceptional skin deposit such as macroglobulinosis cutis that we here report. Physicians should be aware of these clinical manifestations to avoid diagnostic delay.
