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Updated: Jun 11, 2026

Echocardiographic Assessment of the Right Heart in Mice
Published on: November 27, 2013
[Thermodilution vs transesophageal echocardiography for cardiac output measurement in patients with good left
Jarosław Bródka1, Łukasz Tułecki, Magdalena Ciurysek
1Oddział Kardiochirurgii SPSW w Zamościu. jbrodka@poczta.onet.pl
Insights
Transesophageal echocardiography (TEE) accurately estimates cardiac output using continuous-wave and pulse-wave Doppler methods. These TEE measurements closely correlate with thermodilution, confirming TEE
Area of Science:
- Cardiovascular Medicine
- Diagnostic Imaging
- Echocardiography
Background:
- Transesophageal echocardiography (TEE) is a standard diagnostic tool for assessing cardiac output in various cardiac conditions.
- TEE enables real-time estimation of ejection fractions, stroke volumes, and cardiac output, crucial for surgical repair assessment.
- This study investigates novel TEE Doppler methods for cardiac output measurement.
Purpose of the Study:
- To compare cardiac output estimations using aortic continuous-wave Doppler and pulse-wave Doppler via TEE.
- To validate these TEE-derived cardiac output measurements against the established thermodilution method.
Main Methods:
- Cardiac output was measured in 30 adult patients undergoing off-pump coronary artery bypass grafting.
- Aortic valve area was calculated from the transverse short-axis view, assuming a triangular orifice shape.
- Measurements included thermodilution (CO(S-G)), contour wave analysis (CO(CW)), and continuous-wave Doppler (CO(PW)) via TEE.
Main Results:
- Mean cardiac output values were comparable across all three methods: thermodilution (4.59 L/min), CO(CW) (4.49 L/min), and CO(PW) (4.57 L/min).
- A strong positive correlation was observed between thermodilution and CO(CW) (r=0.939, p<0.001).
- A strong positive correlation was also found between thermodilution and CO(PW) (r=0.912, p<0.001).
Conclusions:
- Cardiac output measurements obtained via transesophageal echocardiography using continuous-wave and pulse-wave Doppler are comparable to thermodilution.
- These findings support the use of TEE Doppler techniques as a reliable method for assessing cardiac output in clinical practice.
Background:
Transesophageal echocardiography (TEE) has been regarded as a standard diagnostic method for assessment of cardiac output in aortic dissection, pulmonary embolism, atrial and ventricular septal defects, and acquired valvular defects. It is also a standard method of assessment of the adequacy of their surgical repair. It allows for on-line estimation of ejection fractions and stroke volumes, and calculation of cardiac output. In this prospective study, we compared the cardiac outputs estimated by aortic continuous-wave Doppler, and pulse wave Doppler via transgastric long-axis imaging plane TEE, with results obtained by thermodilution.
Methods:
Cardiac output was determined in thirty adult patients, of both sexes, with good left ventricular function, scheduled for off pump coronary artery bypass grafting. Aortic valve area was plotted from the transverse short-axis view of the valve assuming a triangular shape for the valve orifice.
Results:
Mean cardiac output measured by thermodilution [CO(S-G)] was 4.59 +/- 2.5 L min(-1), compared to 4.49 +/- 1.14 L min(-1) obtained from contour wave [CO(CW)] and 4.57 +/- 1.29 L min(-1) from continuous-wave [CO(PW)] analysis. The correlation coefficient (r) between CO(S-G) and CO(CW) was 0.939, (p < 0.001).The correlation coefficient (r) between CO(S-G) and CO(PW) was 0.912 (p < 0.001).
Conclusions:
Results of cardiac output measurements, obtained from all three methods, were comparable.
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