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Related Concept Videos

Knee Joint01:23

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Ankle Joint01:10

Ankle Joint

The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
Introduction to Joints00:58

Introduction to Joints

The adult human body usually has 206 bones, and except for the hyoid bone in the neck, each bone is connected to at least one other bone. Joints are the location where bones come together. Many joints allow for movement between the bones. At these joints, the articulating surfaces of the adjacent bones can move smoothly against each other. However, the bones of other joints may be joined by connective tissue or cartilage. These joints are designed for stability and provide little or no movement.
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: Jun 11, 2026

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
08:26

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Published on: July 17, 2020

Running and osteoarthritis.

Stuart E Willick1, Pamela A Hansen

  • 1Division of Physical Medicine and Rehabilitation, University of Utah Orthopaedic Center, 590 Wakara Way, Salt Lake City, UT 84108, USA. stuart.willick@hsc.utah.edu

Clinics in Sports Medicine
|July 9, 2010
PubMed
Summary
This summary is machine-generated.

Running offers health benefits but can cause injuries. However, research indicates running does not cause osteoarthritis, the degeneration of articular cartilage. This review focuses on clinical studies refuting this link.

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The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation
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The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation

Published on: July 22, 2019

Related Experiment Videos

Last Updated: Jun 11, 2026

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
08:26

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Published on: July 17, 2020

The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation
09:10

The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation

Published on: July 22, 2019

Area of Science:

  • Sports Medicine
  • Orthopedics
  • Epidemiology

Background:

  • Cardiovascular exercise, like running, provides established health benefits.
  • Running can lead to muscle, tendon, and bone overload injuries.
  • The link between running and osteoarthritis (articular cartilage degeneration) is not well-established.

Purpose of the Study:

  • To review the scientific literature on the association between running and osteoarthritis.
  • To focus on clinical epidemiologic studies examining this relationship.

Main Methods:

  • Systematic review of existing literature.
  • Analysis of clinical epidemiologic studies.

Main Results:

  • The majority of clinical reports do not support an association between running and osteoarthritis.
  • Evidence does not establish running as a cause of articular cartilage degeneration.

Conclusions:

  • Running is not causally linked to osteoarthritis.
  • Further research may explore specific running parameters and osteoarthritis risk, but current evidence refutes a general association.