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Updated: Jun 11, 2026

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete
Published on: January 24, 2025
[Otosyphilis]
Jens Højberg Wanscher1, Christian E Faber
1Odense Universitetshospital, Øre-, Naese- og Halskirurgisk Afdeling F, 5000 Odense C. wanscher@gmail.com
Abstract:
We present a case in which a patient infected with human immunodeficiency virus (HIV) developed a sensorineural hearing loss and tinnitus due to inner-ear syphilis affection. The patient had normal otomicroscopy, tympanometry, ear, nose & throat examination, caloric test and intracranial magnetic resonance imagining. Relevant serological blood samples and lumbal puncture indicated syphilis in its secondary stage or the early latent phase. Audiometry demonstrated a considerable improvement and tinnitus decreased after ten days of treatment with antibiotics and prednisone.
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