Related Experiment Video
Updated: Jun 11, 2026
09:14
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
A video Clinical Global Impression (CGI) in obsessive compulsive disorder.
Abderrahmane Bourredjem1, Antoine Pelissolo, Jean-Yves Rotge
1Pierre and Marie Curie Paris 6 University, ER4, Modelling in Clinical Research, Paris, France.
Psychiatry Research
|July 13, 2010
Summary
The Clinical Global Impression (CGI) scale shows variable reliability in clinical trials, with video scoring improving consistency over time. Multiple clinician ratings are recommended for robust results.
Area of Science:
- Neurology
- Clinical Trials Methodology
Background:
- The Clinical Global Impression (CGI) scale is widely used in clinical research.
- Its reliability, particularly via video scoring, requires further investigation.
Purpose of the Study:
- To assess the reliability of the CGI scale using video recordings.
- To compare reliability between face-to-face and video-based assessments.
- To determine the impact of patient stimulation status on CGI reliability.
Main Methods:
- Analysis of 50 video interviews from a crossover trial on subthalamic nucleus stimulation.
- Six clinicians provided 300 CGI ratings based on video assessments.
- Intraclass correlation (ICC) was calculated to measure inter-rater reliability.
Main Results:
- CGI reliability was lower at the trial's inclusion (ICC=0.30) than at later visits (ICC=0.68).
- Patient stimulation status did not affect CGI reliability.
- Achieving an ICC > 0.8 requires averaging at least two independent video ratings.
Conclusions:
- Video-based CGI assessments are reliable and suitable for clinical trials.
- Standardized protocols, including multiple raters, enhance CGI reliability.
- The study provides evidence for the validity of video CGI as a clinical outcome measure.
Related Concept Videos
01:28Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
01:24Personality Disorders: Dependent and Obsessive-Compulsive
Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
01:27Panic Disorder
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
01:30Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
01:28Social Anxiety Disorder
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
01:30Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are: