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Fast MR cardiac profiling with two-dimensional selective pulses.

H E Cline1, C J Hardy, J D Pearlman

  • 1GE Corporate Research and Development Center, Schenectady, New York 12301.

Magnetic Resonance in Medicine
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

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A novel nuclear magnetic resonance (NMR) pulse sequence creates a real-time cardiac probe, similar to ultrasound, for assessing heart motion and function. This technique offers flexible cardiac imaging beyond traditional ultrasound limitations.

Area of Science:

  • Medical Imaging
  • Biophysics
  • Cardiovascular Magnetic Resonance

Background:

  • M-mode ultrasound is a standard for real-time cardiac assessment.
  • Limitations exist in ultrasound's fixed imaging windows and contrast flexibility.
  • Nuclear Magnetic Resonance (NMR) offers advanced tissue characterization capabilities.

Purpose of the Study:

  • To develop a rapid-profiling NMR pulse sequence for interactive, real-time cardiac M-mode profiling.
  • To create an NMR-based cardiac probe analogous to M-mode ultrasound.
  • To assess cardiac function by measuring heart motion using NMR.

Main Methods:

  • Designed a 2D selective NMR pulse sequence to excite a narrow cylinder of magnetization intersecting the heart.
  • Employed k-space techniques for pulse design with Gaussian or square radial excitation profiles.

Related Experiment Videos

  • Utilized interactive control of rf excitation and gradient waveforms for beam displacement and reorientation, with flow compensation for artifact suppression.

    • Main Results:

    • Phantom images confirmed k-space analysis predictions for excitation profiles.
    • Interactive displacement and reorientation of the NMR beam were demonstrated.
    • Cardiac experiments on volunteers yielded profile plots resembling M-mode echocardiograms, with flexible contrast and non-limited interrogation axes.

    Conclusions:

    • NMR M-mode profiling provides a direct, fast method for measuring heart motion.
    • This technique enables assessment of cardiac function within an MR cardiac exam.
    • Offers advantages over M-mode echocardiography in interrogation flexibility, though temporal resolution is currently lower.