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Related Concept Videos

Liver Regeneration01:24

Liver Regeneration

The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...

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Related Experiment Video

Updated: Jun 10, 2026

Intrasplenic Transplantation of Hepatocytes After Partial Hepatectomy in NOD.SCID Mice
11:24

Intrasplenic Transplantation of Hepatocytes After Partial Hepatectomy in NOD.SCID Mice

Published on: February 10, 2018

Human hepatocyte transplantation.

Anil Dhawan1, Stephen C Strom, Etienne Sokal

  • 1King's Cell Isolation Unit, King's College Hospital, London, UK.

Methods in Molecular Biology (Clifton, N.J.)
|July 21, 2010
PubMed
Summary
This summary is machine-generated.

Hepatocyte transplantation is a promising treatment for acute liver failure and metabolic disorders. This review covers the latest advancements in hepatocyte transplantation from research to clinical application.

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Related Experiment Videos

Last Updated: Jun 10, 2026

Intrasplenic Transplantation of Hepatocytes After Partial Hepatectomy in NOD.SCID Mice
11:24

Intrasplenic Transplantation of Hepatocytes After Partial Hepatectomy in NOD.SCID Mice

Published on: February 10, 2018

Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells
11:44

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Published on: August 29, 2016

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Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine

Published on: November 4, 2018

Area of Science:

  • Hepatology and Regenerative Medicine

Background:

  • Growing interest in hepatocyte transplantation as a clinical option.
  • Potential alternative for acute liver failure and metabolic disorders.
  • Serves as a model for stem cell technology development.

Purpose of the Study:

  • To review the field of hepatocyte transplantation.
  • To cover the journey from laboratory research to clinical practice.

Main Methods:

  • Literature review of hepatocyte transplantation studies.
  • Analysis of current research and clinical applications.

Main Results:

  • Hepatocyte transplantation shows increasing clinical relevance.
  • Established as a proof of concept for cell-based therapies.

Conclusions:

  • Hepatocyte transplantation is a developing field with significant potential.
  • Continued research is crucial for advancing this therapeutic approach.