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Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
Published on: September 2, 2025
Minimally invasive holographic surface scanning for soft-tissue image registration
Ray A Lathrop1, Douglas M Hackworth, Robert J Webster
1Vanderbilt University, Nashville, TN 37235, USA. ray.a.lathrop@vanderbilt.edu
IEEE Transactions on Bio-Medical Engineering
|July 28, 2010
Summary
Conoscopic holography enables minimally invasive soft-tissue surface scanning for surgical guidance. This technology achieved sub-3mm accuracy in guiding surgical needles to subsurface targets, advancing image-guided procedures.
Area of Science:
- Medical Imaging
- Surgical Technology
- Optical Metrology
Background:
- Intrasurgical image guidance has advanced for soft tissues, enabling visualization of instruments and subsurface structures.
- Current methods rely on preoperative image registration to intraoperative surface points, often requiring invasive scanning.
- A noncontact, minimally invasive scanning technology is needed for wider adoption of soft-tissue image guidance.
Purpose of the Study:
- To describe and validate a novel system for minimally invasive soft-tissue surface scanning using conoscopic holography.
- To assess the system's suitability for biological tissues and compare its performance to existing clinical methods.
- To demonstrate the system's capability in guiding surgical instruments to subsurface targets.
Main Methods:
- Development of a tracked, off-the-shelf conoscopic holography system.
- Validation experiments involving ex vivo biological and phantom tissues.
- Comparison of surface scan quality with clinically used laser range scanning systems.
- Experimental demonstration of needle guidance to subsurface targets.
Main Results:
- Conoscopic holography is suitable for scanning biological tissues, yielding surface scans comparable to open-surgery laser range scanners.
- The system demonstrated effective minimally invasive surface scanning through a single laparoscopic port.
- Surgical needle guidance to subsurface targets achieved an average tip error of less than 3 mm.
Conclusions:
- Conoscopic holography presents a viable noncontact, minimally invasive solution for soft-tissue surface scanning in surgical guidance.
- This technology can enhance the adoption of image-guided soft-tissue procedures.
- The demonstrated accuracy supports its potential for precise surgical interventions.

