Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Actin Polymerization01:42

Actin Polymerization

Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶  nucleation, elongation, and steady-state phase.
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight actin...
Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
Actin Polymerization and Cell Motility01:13

Actin Polymerization and Cell Motility

Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Earlier biomarkers in fish evidencing stress responses to metal and organic pollution along the Doce River Basin.

Environmental pollution (Barking, Essex : 1987)·2023
Same author

Cauda Equina and Filum Terminale Arteriovenous Fistulas: Anatomic and Radiographic Features.

AJNR. American journal of neuroradiology·2020
Same author

Electrochemical microdevices for rapid and on-site determination of the minimum inhibitory concentration of antibiotics.

The Analyst·2017
Same author

Hypertrophy of the extra-articular tendon of the long head of biceps correlates with the location and size of a rotator cuff tear.

The bone & joint journal·2017
Same author

Effect of Gender Differences on Transplant Kidney Function.

Transplantation proceedings·2017
Same author

Suspected Metallic Embolism following Endovascular Treatment of Intracranial Aneurysms.

AJNR. American journal of neuroradiology·2016
Same journal

Full robotic endovascular treatment for various head and neck hemorrhagic lesions.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2026
Same journal

Publisher's note.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2026
Same journal

Expression of Concern.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2026
Same journal

Erratum to "Initial experience with the antithrombogenic-coated CARESTOstent for venous sinus stenting for idiopathic intracranial hypertension: A multicenter study".

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2026
Same journal

Transcirculation retrograde deployment of Neuroform Atlas stent-assisted coil embolization for a superior cerebellar artery aneurysm.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2026
Same journal

Retrieval of a fractured radial access catheter from the axillary artery.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2026
See all related articles

Related Experiment Video

Updated: Jun 10, 2026

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators
14:42

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators

Published on: April 25, 2020

The development for polymer actuator active catheter system.

S Sewa1, K Onishi, K Oguro

  • 1Japan Chemical Innovation Institute, Midorigaoka, Ikeda, Osaka; Japan.

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
|July 29, 2010
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel electric stimuli polymer-metal composite actuator for active catheter systems. This soft, lightweight actuator bends 90 degrees with 3 volts, enabling precise control in medical procedures.

More Related Videos

Rapid Manufacturing of Thin Soft Pneumatic Actuators and Robots
08:47

Rapid Manufacturing of Thin Soft Pneumatic Actuators and Robots

Published on: November 8, 2019

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

Related Experiment Videos

Last Updated: Jun 10, 2026

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators
14:42

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators

Published on: April 25, 2020

Rapid Manufacturing of Thin Soft Pneumatic Actuators and Robots
08:47

Rapid Manufacturing of Thin Soft Pneumatic Actuators and Robots

Published on: November 8, 2019

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Robotics

Background:

  • Development of advanced materials for minimally invasive medical devices.
  • Need for precise and controllable actuators in surgical tools.
  • Limitations of current catheter technologies in navigating complex vasculature.

Purpose of the Study:

  • To develop and evaluate a novel polymer-metal composite actuator for active catheter systems.
  • To demonstrate the feasibility of using electric stimuli for precise catheter tip control.
  • To assess the performance of the active catheter in preclinical animal models.

Main Methods:

  • Fabrication of a polymer-metal composite actuator using ion exchange polymer and gold electrodes.
  • Application of a 3-volt pulse voltage to induce actuator bending.
  • Integration of the polymer actuator into a prototype active catheter using Micro-Electro-Mechanical Systems (MEMS) technologies.
  • In vivo testing in canine models to evaluate directional control and bending accuracy.

Main Results:

  • The polymer-metal composite actuator demonstrated a rapid 90-degree bend upon application of a 3-volt pulse.
  • The active catheter prototype exhibited precise, externally controlled bending capabilities.
  • Animal testing confirmed effective navigation and accurate angle control at vascular bifurcations and aneurysms.

Conclusions:

  • A novel, small-size, lightweight, and soft polymer actuator material has been successfully developed.
  • The developed polymer actuator technology enables the creation of advanced active catheters for interventional radiology.
  • Preclinical trials indicate significant potential for improving surgical outcomes in complex vascular interventions.