Related Experiment Video
Updated: Jun 10, 2026

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits
Published on: February 28, 2025
[Generous use of opioids is advantageous for infants and children--Pro]
1Abteilung für Anästhesieund Intensivmedizin der Klinik Hallerwiese/Cnopf'sche Kinderklinik (Diakonie Neuendettelsau), Nürnberg. Karin.Becke@diakonieneuendettelsau.de
Insights
In pediatric anesthesia, multimodal analgesia balances safety and comfort. Opioids should be used more liberally, not restrictively, to effectively manage pediatric pain.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Pharmacology
Context:
- Modern pediatric anesthesia prioritizes patient safety, pain reduction, and comfort.
- Multimodal analgesia combines regional/local anesthesia, non-opioids, and opioids.
- Opioid use in children is often restricted due to unsubstantiated fears of side effects.
Purpose:
- To advocate for a more liberal yet considered use of opioids in pediatric anesthesia.
- To highlight the undertreatment of pain in pediatric patients.
- To outline the requirements for a professional pediatric pain service.
Summary:
- Opioids can be used more generously in pediatric anesthesia to improve pain management.
- Effective pain control requires understanding pediatric physiology and pharmacokinetics.
- A professional pain service needs monitoring capabilities and side effect management protocols.
Impact:
- Improved pain management in pediatric patients.
- Reduced incidence of undertreated pain in children undergoing surgery.
- Enhanced patient safety and comfort during the perioperative period.
Abstract:
Modern perioperative anesthesia regimen in pediatric anesthesia focus on patient safety, pain reduction and patient comfort. Multimodal analgesia is based on regional/local anesthesia, non opioids and opioids. The use of opioids is traditionally much more restrictive than in adult anesthesia because of mostly unsubstantiated fear of serious side effects. As pain is still undertreated in pediatric anesthesia, opioids should be used generously but well-considered. Requirements for a professional pain service are: knowledge of the physiologic and pharmacokinetic specialities of children, possibility of monitoring (f.e. postanesthetic care unit) and prophylaxis and therapy of side effects.
Related Concept Videos
Drug Dosing: Infants and Children
Opioid Analgesics: Morphine and Other Natural Cogeners
Factors Affecting Drug Response: Overview
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Pharmacokinetics in Pediatric Patients: Drug Excretion
Analgesia and Pain Management