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Published on: March 26, 2018

Transcatheter aortic valve implantation in high-risk patients with severe aortic stenosis

Hidehiko Hara1, Robert S Schwartz

  • 1Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan. harahide@aol.com

Circulation Journal : Official Journal of the Japanese Circulation Society
|July 31, 2010
PubMed

Insights

Transcatheter aortic valve implantation (TAVI) offers a less invasive treatment for severe aortic stenosis, especially in elderly patients. This procedure demonstrates high success rates, providing a viable alternative to traditional surgery.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Devices

Background:

  • Severe aortic stenosis (AS) poses significant treatment challenges, particularly for elderly patients deemed high-risk for conventional surgery.
  • High complication rates associated with surgical aortic valve replacement lead to reluctance in treating elderly patients.
  • The increasing prevalence of severe AS in aging populations necessitates alternative treatment options.

Purpose of the Study:

  • To review the methods and devices used in transcatheter aortic valve implantation (TAVI).
  • To highlight TAVI as a less invasive alternative for severe aortic stenosis treatment in high-risk patients.
  • To provide an overview of TAVI technologies anticipated for future availability in Japan.

Main Methods:

  • Review of percutaneous transcatheter aortic valve implantation (TAVI) techniques.
  • Examination of early TAVI devices, including the Edwards SAPIEN valve and the Corevalve ReValving system.
  • Analysis of global patient data and procedural success rates up to April 2010.

Main Results:

  • Transcatheter aortic valve implantation (TAVI) has been performed in over 15,000 patients worldwide.
  • High acute success rates reported for TAVI: up to 95.4% (transfemoral) and 92.7% (transapical) for Edwards SAPIEN.
  • Excellent success rates of 98.2% reported for the Corevalve ReValving system in experienced centers.

Conclusions:

  • Transcatheter aortic valve implantation (TAVI) is an established and effective treatment for severe aortic stenosis in high-risk patients.
  • TAVI offers a minimally invasive approach with high procedural success rates, expanding treatment options for elderly individuals.
  • Several TAVI devices are expected to become available in Japan, further advancing cardiac care.

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