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Nirosha Paramanathan¹, Arik Nemet, Scott E Lee

¹Drummoyne Eye Surgical Centre, Sydney, Australia.

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|August 5, 2010

Summary

This study found that a modified Jones dye test, along with fluorescein dye disappearance tests, strongly correlates with lacrimal scintigraphy for diagnosing epiphora (excessive tearing) causes.

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Area of Science:

Ophthalmology
Medical Diagnostics

Background:

Epiphora, or excessive tearing, can significantly impact quality of life.
Accurate diagnosis of the underlying cause of epiphora is crucial for effective treatment.

Purpose of the Study:

To evaluate the correlation between lacrimal scintigraphy and a combination of modified Jones primary dye test, fluorescein dye disappearance test (DDT), and Jones secondary dye test.
To assess the diagnostic accuracy of these dye tests in identifying the causes of epiphora.

Main Methods:

A prospective clinical trial included 39 patients (65 eyes) presenting with epiphora, excluding those with specific contraindications.
Patients underwent fluorescein DDT and a modified Jones primary dye test (JDT1).
A Jones secondary dye test was performed if JDT1 was negative. Patients were referred for lacrimal scintigraphy unless anatomical obstruction was definitively identified.

Main Results:

A strong positive correlation (91%) was observed between the diagnoses from the modified dye testing and lacrimal scintigraphy.
The interrater reliability for the dye tests was found to be good (κ = 0.770).

Conclusions:

The modified Jones primary dye test, in conjunction with fluorescein DDT and Jones secondary dye test, demonstrates strong correlation with lacrimal scintigraphy.
This combination of dye tests is a reliable method for diagnosing lacrimal drainage system dysfunction causing epiphora.