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Auto-immune spondylodiscitis associated with collagen induced arthritis in rats: high field MRI findings
P Gillet1, P Fener, J M Escanyé
1Department of Pharmacology, URA CNRS 1288, Université de Nancy, Vandoeuvre Les Nancy.
Agents and Actions. Supplements
|January 1, 1991
Abstract:
The spinal involvement of the tail was studied in Wistar Furth rats immunized with bovine native type II collagen. Focal caudal autoimmune spondylodiscitis occurred 5 weeks after sensitization, as assessed histopathologically. High field Magnetic Resonance Imaging (MRI) was useful in depicting these caudal abnormalities that were related to juxta-diskal enthesitis. The occurrence of such inflammatory enthesopathies could serve as an experimental approach for physiopathological and therapeutical studies of spondylarthropathies.