Related Experiment Video

Updated: Jun 10, 2026

Experimental Model to Evaluate Resolution of Pneumonia
09:49

Experimental Model to Evaluate Resolution of Pneumonia

Published on: February 17, 2023

[Acute fibrinous and organizing pneumonia]

Cláudia Santos1, Fátima Fradinho, Alexandra Catarino

  • 1Serviço de Pneumologia dos Hospitais da Universidade de Coimbra. claudiaraimundo80@gmail.com

Revista Portuguesa De Pneumologia
|August 12, 2010
PubMed

Insights

Acute Fibrinous and Organizing Pneumonia (AFOP) is a distinct interstitial lung disease. This review clarifies its unique features and differentiates it from other acute lung injury patterns.

Area of Science:

  • Pulmonary Medicine
  • Histopathology
  • Interstitial Lung Diseases

Background:

  • Acute Fibrinous and Organizing Pneumonia (AFOP) is a distinct histologic pattern of acute lung injury.
  • It was first described by Beasley in 2002 and is characterized by intra-alveolar fibrin and organizing pneumonia.
  • AFOP presents with acute or subacute symptoms, distinguishing it from other acute pulmonary lesions.

Observation:

  • This review synthesizes current literature on AFOP.
  • A specific clinical case of a 44-year-old patient with AFOP is presented.
  • The case highlights unusual imaging features and clinical outcomes associated with AFOP.

Findings:

  • AFOP is histologically defined by intra-alveolar fibrin "balls" and diffuse organizing pneumonia.
  • It differs from Diffuse Alveolar Damage (DAD), Organizing Pneumonia (OP), and Eosinophilic Pneumonia (EP).
  • The presented case demonstrates atypical radiological findings and a unique patient outcome.

Implications:

  • Understanding AFOP's distinct characteristics is crucial for accurate diagnosis and patient management.
  • Differentiating AFOP from other acute lung injuries impacts treatment strategies.
  • Further research into AFOP's pathogenesis and clinical course is warranted.

More Related Videos

Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa07:27

Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa

Published on: July 12, 2018

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

Related Concept Videos

Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.