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Updated: Jun 10, 2026
A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft
Published on: February 14, 2022
Heart transplantation
Maria G Crespo-Leiro1, Eduardo Barge-Caballero, Raquel Marzoa-Rivas
1Unidad de Insuficiência Cardíaca y Trasplante Cardíaco, Hospital Universitário A Coruña, La Coruña, Spain. marisa.crespo.leiro@sergas.es
Purpose Of Review:
This paper briefly and subjectively reviews a number of the modest or tentative, but noteworthy, advances in heart transplantation that have been made during the past 18 months or so.
Recent Findings:
The advances reviewed concern the selection of recipients, the management of the heart transplantation waiting list, the management of donors, post-heart transplant monitoring of immunological status, the early diagnosis of rejection, the role of mammalian target of rapamycine inhibitors and induction agents, and the definition and grading of cardiac allograft vasculopathy.
Summary:
The findings reviewed indicate progress in the clarification of issues that were in most cases already being investigated. Further studies will in general be needed before corresponding measures are adopted in clinical practice.
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