Related Experiment Video
Updated: Jun 10, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Acute oral potassium overdose: the role of hemodialysis
George M Bosse1, Melissa A Platt, Stephen D Anderson
1Department of Emergency Medicine, University of Louisville, 530 S. Jackson Street, Louisville, KY, 40202, USA. george.bosse@nortonhealthcare.org
Introduction:
Hyperkalemia is a common condition, particularly in the setting of renal dysfunction. Hyperkalemia due to intentional oral potassium overdose is not commonly reported.
Case Report:
We present a case of acute intentional potassium overdose in a patient with normal renal function resulting in significant hyperkalemia, with a maximum serum potassium concentration of 11 mEq/L. Despite an initial course complicated by various unstable cardiac rhythms, including ventricular tachycardia, ventricular fibrillation, and pulseless electrical activity, the patient was discharged from the hospital neurologically intact. Treatment for hyperkalemia included hemodialysis.
Discussion:
The role of dialysis in potassium overdose is poorly defined.
Conclusion:
Based on this case and a review of the medical literature, we recommend hemodialysis for cases of potassium overdose with hemodynamic instability and significantly elevated serum potassium concentrations that do not respond promptly to medical therapy. Hemodialysis should also be considered in cases with underlying renal dysfunction.
Related Concept Videos
Acute Kidney Injury V: Interprofessional Care
Antihypertensive Drugs: Potassium-Sparing Diuretics
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Acute Kidney Injury VI: Nursing Management
Hemodialysis II: Procedure and Complications