Related Experiment Video
Updated: Jun 10, 2026

The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies
Published on: February 12, 2015
Radioisotopes as Political Instruments, 1946-1953
1Department of History, Princeton University. 136 Dickinson Hall, Princeton, NJ 08544-1174. creager@princeton.edu.
Abstract:
The development of nuclear "piles," soon called reactors, in the Manhattan Project provided a new technology for manufacturing radioactive isotopes. Radioisotopes, unstable variants of chemical elements that give off detectable radiation upon decay, were available in small amounts for use in research and therapy before World War II. In 1946, the U.S. government began utilizing one of its first reactors, dubbed X-10 at Oak Ridge, as a production facility for radioisotopes available for purchase to civilian institutions. This program of the U.S. Atomic Energy Commission was meant to exemplify the peacetime dividends of atomic energy. The numerous requests from scientists outside the United States, however, sparked a political debate about whether the Commission should or even could export radioisotopes. This controversy manifested the tension in U.S. politics between scientific internationalism as a tool of diplomacy, associated with the aims of the Marshall Plan, and the desire to safeguard the country's atomic monopoly at all costs, linked to American anti-Communism. This essay examines the various ways in which radioisotopes were used as political instruments-both by the U.S. federal government in world affairs, and by critics of the civilian control of atomic energy-in the early Cold War.
Related Concept Videos
Isotopes and Radioisotopes
An isotope containing more...
Radioactivity and Nuclear Equations
A nuclide of an element has a specific number of protons and...
Nuclear Transmutation
Nuclear Stability
To hold positively charged protons together in the...
Radioactive Decay and Radiometric Dating
Types of Radioactivity
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:

