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Related Concept Videos

Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
Classification of Epithelial Tissues: Stratified Epithelium01:29

Classification of Epithelial Tissues: Stratified Epithelium

Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
Classification of Epithelial Tissues: Glandular Epithelium01:20

Classification of Epithelial Tissues: Glandular Epithelium

The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Epithelial Tissues and Their Functions01:23

Epithelial Tissues and Their Functions

Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
Epithelial tissues provide the body's first line of protection from physical, chemical, and...
Classification of Epithelial Tissues: Simple Epithelium01:30

Classification of Epithelial Tissues: Simple Epithelium

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...

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Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
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Epithelioid sarcoma: a review and update.

Joseph F Sobanko1, Lindsay Meijer, Thomas P Nigra

  • 1Dr. Sobanko is Chief Resident, Dermatology, Georgetown University Hospital/Washington Hospital Center, Washington, DC.

The Journal of Clinical and Aesthetic Dermatology
|August 24, 2010
PubMed
Summary
This summary is machine-generated.

Epithelioid sarcoma, a rare soft tissue tumor, often presents subtly, leading to misdiagnosis and inadequate treatment. Early recognition in young males with slow-growing distal extremity tumors is crucial for better outcomes.

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Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Epithelioid sarcoma is a rare, high-grade soft tissue malignancy.
  • It characteristically shows propensity for local recurrence, lymph node metastasis, and distant spread.
  • Its insidious presentation often leads to initial misdiagnosis as benign conditions.

Purpose of the Study:

  • To review the clinical and histological features of epithelioid sarcoma.
  • To highlight the diagnostic challenges and emphasize the importance of early recognition.
  • To discuss prognostic factors and current treatment strategies.

Main Methods:

  • Review of clinical presentations.
  • Analysis of histological findings.
  • Discussion of prognostic indicators and treatment modalities.

Main Results:

  • Epithelioid sarcoma can present deceptively, mimicking benign lesions.
  • Delayed diagnosis is common due to its subtle and slow-growing nature.
  • Factors like local recurrence, lymph node involvement, and tumor width impact prognosis.

Conclusions:

  • Clinicians must consider epithelioid sarcoma in young males with slow-growing distal extremity tumors.
  • Prompt diagnosis and appropriate treatment are essential due to the poor prognosis.
  • Management involves radical excision, sentinel lymph node biopsy, and radiation therapy.