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Related Concept Videos

Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Rab Proteins01:14

Rab Proteins

Rab proteins constitute the largest family of monomeric GTPases, of which 70 members are present in humans. Rab proteins and their effectors regulate consecutive stages of vesicle transport such as vesicle transport, docking, and fusion to the correct recipient membrane.
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Size and Structure of Viral Genomes01:26

Size and Structure of Viral Genomes

Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

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Related Experiment Video

Updated: Jun 10, 2026

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
08:10

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses

Published on: May 2, 2019

[Rabies in Poland in 2008].

Małgorzata Sadkowska-Todys1, Bozena Kucharczyk

  • 1Zakład Epidemiologii, Narodowego Instytutu Zdrowia Publicznego - Państwowego Zakładu Higieny w Warszawie. mtodys@pzh.gov.pl

Przeglad Epidemiologiczny
|August 25, 2010
PubMed
Summary

Rabies vaccination campaigns in Poland have reduced animal rabies cases since 1993. However, ongoing risks from wild and domestic animals necessitate continued vigilance and public health measures.

Area of Science:

  • Veterinary epidemiology
  • Zoonotic disease control
  • Public health

Context:

  • Poland reported 28 animal rabies cases in 2008.
  • Mass oral vaccination of wild animals against rabies initiated in 1993 has shown positive effects.
  • Rabies reservoirs persist in wild and domestic animals, particularly in eastern Poland.

Purpose:

  • To assess the impact of the oral vaccination program on rabies epizootic situation in Poland.
  • To analyze the reasons for post-exposure rabies prophylaxis in humans.

Summary:

  • Despite vaccination, 28 animal rabies cases were reported in Poland in 2008.
  • In 2008, 6,495 individuals received rabies vaccination, with 89% due to potential exposure to rabid animals.
  • The oral vaccination program has positively influenced the rabies epizootic situation, primarily through fox immunization.

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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

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A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies
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A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Related Experiment Videos

Last Updated: Jun 10, 2026

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
08:10

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses

Published on: May 2, 2019

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
10:26

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Published on: August 18, 2023

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies
04:10

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Impact:

  • Demonstrates the effectiveness of oral rabies vaccination in wildlife.
  • Highlights the continued need for rabies surveillance and control measures in both wild and domestic animal populations.
  • Informs public health strategies regarding human rabies prevention following animal contact.