Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 9, 2026

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels
08:37

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

Published on: July 3, 2025

[Cryosurgery in diffuse hepatic diseases].

I V Sleta, N A Chizh, D G Lutsenko

    Klinichna Khirurhiia
    |August 26, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same authorSame journal

    Klinichna khirurhiia·2018
    Same author

    [TECHNIQUE OF EXPERIMENTAL STENTING OF VESSELS FOR INVESTIGATIONS IN VIVO].

    Klinichna khirurhiia·2016
    Same author

    [Investigation of adhesive properties of polypropylene net prosthesis "ESPERA"].

    Klinichna khirurhiia·2015
    Same author

    [Effect of different types of cold acclimation on osmotic fragility and sphericity index of rat erythrocytes].

    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova·2014
    Same author

    [Effect of C60 fullerene on metabolic and proliferative activity of PKE cell line].

    Ukrainian biochemical journal·2014
    Same author

    The use of catalytic carbon deposits as 3D carriers for human bone marrow stromal cells.

    Bulletin of experimental biology and medicine·2012
    Same journal

    Klinichna khirurhiia·2018
    Same journal

    Klinichna khirurhiia·2018
    Same journal

    Klinichna khirurhiia·2018
    Same journal

    Klinichna khirurhiia·2018
    Same journal

    Klinichna khirurhiia·2018
    See all related articles

    Combined cryosurgical methods, including cryohepatodestruction (CHD) and periarterial cryodenervation of the hepatic artery (CDHA), significantly enhance liver restoration in experimental cirrhosis. This dual approach accelerates healing compared to individual treatments.

    Area of Science:

    • Regenerative Medicine
    • Surgical Innovation
    • Hepatology

    Context:

    • Experimental cirrhosis model in 215 male rats.
    • Histological and biomicroscopic analysis of liver tissue.
    • Evaluation of cryosurgical techniques on liver restoration.

    Purpose:

    • To compare the efficacy of cryohepatodestruction (CHD) and periarterial cryodenervation of the hepatic artery (CDHA) individually and in combination.
    • To assess the impact of these cryosurgical methods on the dynamics of hepatic restoration processes in experimental cirrhosis.
    • To determine if concomitant application of CHD and CDHA enhances liver recovery more than monotherapy.

    Summary:

    • Periarterial cryodenervation of the hepatic artery (CDHA) improves hepatic microcirculation, increasing sinusoidal vessel diameter and vascular bed area.

    More Related Videos

    Bulk Droplet Vitrification for Primary Hepatocyte Preservation
    11:07

    Bulk Droplet Vitrification for Primary Hepatocyte Preservation

    Published on: October 25, 2019

    Thermal Ablation for the Treatment of Abdominal Tumors
    07:16

    Thermal Ablation for the Treatment of Abdominal Tumors

    Published on: March 7, 2011

    Related Experiment Videos

    Last Updated: Jun 9, 2026

    Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels
    08:37

    Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

    Published on: July 3, 2025

    Bulk Droplet Vitrification for Primary Hepatocyte Preservation
    11:07

    Bulk Droplet Vitrification for Primary Hepatocyte Preservation

    Published on: October 25, 2019

    Thermal Ablation for the Treatment of Abdominal Tumors
    07:16

    Thermal Ablation for the Treatment of Abdominal Tumors

    Published on: March 7, 2011

  • Dosed cryohepatodestruction (CHD) effectively stimulates reparative processes in pathologically altered liver tissue.
  • Simultaneous application of CHD and CDHA significantly accelerates and improves the degree of liver restoration in cirrhotic rats compared to using either method alone.

    • Impact:

    • Demonstrates a synergistic effect of combined cryosurgical interventions for liver regeneration.
    • Provides evidence for enhanced therapeutic outcomes in treating experimental liver cirrhosis.
    • Highlights potential for novel, combined cryosurgical strategies in managing liver disease.