[TECHNIQUE OF EXPERIMENTAL STENTING OF VESSELS FOR INVESTIGATIONS IN VIVO].

Area of Science:

• Vascular surgery
• Preclinical research
• Biomedical engineering

Context:

• Introducing new vascular stenting systems requires robust preclinical validation.
• Current methods may involve complex procedures and specialized equipment.
• Standardized animal models are crucial for evaluating novel medical devices.

Purpose:

• To present a simplified, cost-effective in vivo method for vascular stent implantation in rabbits.
• To detail the surgical aspects and post-operative assessment of stent placement.
• To establish a reproducible technique for preclinical evaluation of vascular stents.

Summary:

• A novel method for implanting vascular stents in the rabbit abdominal aorta using a peripheral vascular catheter is described.
• The procedure includes surgical considerations, assessment of cardiac and aortic function, and morphometric analysis of the stent after 30 days.
• This technique simplifies surgical procedures, reduces experimental costs, and does not require specialized endovascular equipment.

Impact:

• Facilitates preclinical research on vascular stents by offering a more accessible and economical approach.
• Enables researchers in general surgery settings to conduct experimental investigations on stenting techniques.
• Contributes to the development and validation of new vascular stenting technologies.