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Updated: Jun 9, 2026

10:09
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
Published on: June 30, 2018
Complete surface control of peptide nanospheres with detachable and attachable polymer brush layers
Tomonori Waku1, Masahiro Matsumoto, Michiya Matsusaki
1Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita 565-0871, Japan.
Abstract:
The surfaces of biodegradable peptide nanospheres with density-controllable poly(ethylene glycol) (PEG) brush layers were amenable to high levels of control, from hydrophilic 'stealth' properties to hydrophobic adsorptive properties depending on the PEG density in response to environmental conditions -'intelligent' properties that are expected to be useful for novel drug delivery systems.

