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[Protective effect of hyperbaric hypoxygenation for paraquat poisoning in the rat]
R Manieri1, R Bronzi, A Grilli
1Service d'Anesthésiologie et Réanimation Hôpital S. Camillo, U.L.S. RM10, Rome, Italie.
Journal De Toxicologie Clinique Et Experimentale
|September 1, 1990
Abstract:
The effect to paraquat in normobaric conditions and hyperbaric conditions with either a normal or low (10%) oxygen percentage was investigated in rats. Results showed that hyperbaric conditions increased the toxic effect of paraquat on the lung. By contrast, in hypoxic-hyperbaric conditions, the toxic effect of paraquat was decreased either clinically or macro-/microscopically, and lung injury was reduced.