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Cysteine-based redox switches in enzymes.

Chananat Klomsiri1, P Andrew Karplus, Leslie B Poole

  • 1Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

Antioxidants & Redox Signaling
|August 31, 2010
PubMed
Summary

Enzymes are regulated by posttranslational modifications, including redox modifications of cysteine residues. These redox events are integral to cell signaling and often work with phosphorylation, with peroxiredoxins playing key roles.

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