Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Other Factors Affecting Respiration Centers01:17

Other Factors Affecting Respiration Centers

Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical level,...
Neural Control of Respiration01:18

Neural Control of Respiration

The neural regulation of respiration is a meticulously coordinated process primarily controlled by the respiratory centers located within the brainstem. These centers, composed of specialized neurons, transmit nerve impulses that control the contraction and relaxation of our respiratory muscles.
Respiratory Centers in the Brainstem
Two primary areas comprise the respiratory center: the medullary respiratory center in the medulla oblongata and the pontine respiratory group in the pons. The...
Physiology of Respiration II: Neurogenic Control of Respiration01:22

Physiology of Respiration II: Neurogenic Control of Respiration

The neurogenic control of respiration coordinates various neural networks and pathways to regulate breathing rate and depth, meeting the body's oxygen and carbon dioxide exchange requirements. This system adapts to physiological and environmental conditions, ensuring optimal breathing patterns.
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Mechanism of Breathing I: Inspiration01:30

Mechanism of Breathing I: Inspiration

Introduction to Inspiration: The Respiratory System in Action
The respiratory system, an essential network for breathing, comprises the conducting and respiratory zones, each playing a crucial role in the overall process of respiration. Let us explore the detailed mechanism of inspiration, or inhalation, which is the first phase of the respiratory cycle.
Pathway of Air during Inspiration
During inspiration, air enters our body through the nose or mouth and moves through the conducting zone,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Sleep disorders in imprinting disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2025
Same author

[The resistance of low brainstem tissue to free radical oxidation in rats during periodic breathing following hydroxybutyrate treatment].

Patologicheskaia fiziologiia i eksperimental'naia terapiia·2014
Same author

[Respiratory reactions on microinjections of GABA and baclofen into the Bötzinger complex and the pre-Bötzinger complex in rats].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova·2012
Same author

Effects of electrical stimulation of respiratory center in the event of termination of its natural rhythmic activity.

Bulletin of experimental biology and medicine·2011
Same author

[Experience with vascular biografts "KemAngioprotez" in reconstructive surgery of lower-limb major arteries].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery·2009
Same author

[Expression of N-acyl-homoserine lactonase AiiA gene affects properties of rhizospheric strain Pseudomonas chlororaphis 449].

Genetika·2009

Related Experiment Video

Updated: Jun 9, 2026

Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity
11:34

Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity

Published on: January 10, 2013

[Electrical stimulation of breathing].

V A Safonov, N N Tarasova

    Fiziologiia Cheloveka
    |September 1, 2010
    PubMed
    Summary

    Breathing electrostimulation offers medical advantages. This review details methods, devices, electrode placement, and parameter effects for respiratory muscle training.

    Area of Science:

    • Medical Technology
    • Respiratory Physiology
    • Rehabilitation

    Context:

    • Breathing electrostimulation is an emerging technique for respiratory muscle training.
    • Understanding its various methods and parameters is crucial for effective clinical application.

    Purpose:

    • To provide a comprehensive overview of breathing electrostimulation (BES) techniques.
    • To analyze the advantages and disadvantages of different BES methods.
    • To detail electrostimulator descriptions, electrode placements, and parameter influences.

    Summary:

    • Generalized data on diverse breathing electrostimulation methods, including electrostimulator descriptions, electrode site variations, and parameter influences.
    • Evaluated the merits and demerits of each presented electrostimulation approach.

    More Related Videos

    An Implantable System For Chronic In Vivo Electromyography
    09:52

    An Implantable System For Chronic In Vivo Electromyography

    Published on: April 21, 2020

    Placement of Extracranial Stimulating Electrodes and Measurement of Cerebral Blood Flow and Intracranial Electrical Fields in Anesthetized Mice
    06:34

    Placement of Extracranial Stimulating Electrodes and Measurement of Cerebral Blood Flow and Intracranial Electrical Fields in Anesthetized Mice

    Published on: June 2, 2023

    Related Experiment Videos

    Last Updated: Jun 9, 2026

    Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity
    11:34

    Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity

    Published on: January 10, 2013

    An Implantable System For Chronic In Vivo Electromyography
    09:52

    An Implantable System For Chronic In Vivo Electromyography

    Published on: April 21, 2020

    Placement of Extracranial Stimulating Electrodes and Measurement of Cerebral Blood Flow and Intracranial Electrical Fields in Anesthetized Mice
    06:34

    Placement of Extracranial Stimulating Electrodes and Measurement of Cerebral Blood Flow and Intracranial Electrical Fields in Anesthetized Mice

    Published on: June 2, 2023

  • Highlighted the benefits of applying breathing electrostimulation in medical settings.
  • Impact:

    • Provides a foundational resource for clinicians and researchers exploring respiratory electrostimulation.
    • Facilitates informed decision-making regarding the selection and implementation of BES therapies.
    • Supports the advancement of non-invasive respiratory support and rehabilitation strategies.