Related Experiment Video
Updated: Jun 9, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
[Fracture risk in secondary osteoporosis]
Shozo Yano1, Toshitsugu Sugimoto
1Department of Internal Medicine 1, Shimane University Faculty of Medicine.
Abstract:
In this review, we focused on diabetes mellitus (DM) , chronic kidney disease (CKD) , and glucocorticoid-induced osteoporosis (GIO) , which frequently occurred in the clinical settings, to discuss hip fracture risk. In DM, either type 1 or type 2, fracture risk is elevated probably due to deteriorated bone quality and increased frequency of falls, because the risk is much higher than that expected by bone density. In CKD, especially in patients undergoing dialysis therapy, high risks of fractures in younger people and of mortality after fractures are striking. Even mild to moderate renal dysfunction has recently been reported to elevate fracture risk. In GIO, we reviewed some papers in terms of relationship between doses and duration of corticosteroids and fracture risk.
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Secondary Spinal Cord Injury llI: Pathophysiology
Bone Remodeling
Osteoclasts in Bone Remodeling