Related Experiment Video
Updated: Jun 9, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
Published on: February 3, 2013
Goodness-of-fit tests for correlated paired binary data
Man-Lai Tang1, Yan-Bo Pei, Weng-Kee Wong
1Department of Mathematics, Hong Kong Baptist University, Hong Kong, China.
Abstract:
We review a few popular statistical models for correlated binary outcomes, present maximum likelihood estimates for the model parameters, and discuss model selection issues using a variety of goodness-of-fit test statistics. We apply bootstrap strategies that are computationally efficient to evaluate the performance of goodness-of-fit statistics and observe that generally the power and the type I error rate of the goodness-of-fit statistics depend on the model under investigation. Our simulation results show that careful choice of goodness-of-fit statistics is an important issue especially when we have a small sample and the outcomes are highly correlated. Two biomedical applications are included.
Related Concept Videos
Goodness-of-Fit Test
Expected Frequencies in Goodness-of-Fit Tests
Statistical Methods to Analyze Parametric Data: Student t-Test and Goodness-of-Fit Test
The Student's t-test is a statistical test that examines if there is a statistically significant difference between the means of two groups. This test is instrumental when dealing with data...
Wilcoxon Signed-Ranks Test for Matched Pairs
Test for Homogeneity
Sign Test for Matched Pairs
To conduct the sign test, we first calculate the differences in value between...
