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Updated: Jun 9, 2026
11:17
Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
[Child pleuropulmonary blastoma]
F Dommange-Romero1, S Collardeau-Frachon, F Hameury
1Institut d'hématologie et oncologie pédiatrique, Lyon, France. florence.dommange-romero@chu-lyon.fr
Bulletin Du Cancer
|September 4, 2010
Summary
Pleuropulmonary blastoma is a rare pediatric thoracic tumor. Treatment depends on histological type, ranging from surgery for Type I to surgery and chemotherapy for aggressive Types II and III.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
Context:
- Pleuropulmonary blastoma (PPB) is an extremely rare and aggressive thoracic tumor exclusively found in children.
- Initial symptoms are often non-specific respiratory issues, with imaging revealing a thoracic mass.
Purpose:
- To outline the diagnosis, histological classification, and treatment strategies for pediatric pleuropulmonary blastoma.
- To emphasize the importance of complete surgical resection and surveillance for associated conditions.
Summary:
- Diagnosis is confirmed via anatomopathology or biopsy, revealing three histological types: Type I (cystic), Type II (cystic and solid), and Type III (solid).
- Type I PPB is less aggressive and treated surgically. Types II and III are highly aggressive, requiring surgery combined with polychemotherapy.
- Complete surgical excision is crucial for all types. Surveillance includes bone scan, brain imaging, and abdominal ultrasound due to potential familial predisposition and associated renal lesions.
Impact:
- Provides a clear diagnostic and treatment algorithm for pleuropulmonary blastoma.
- Highlights the need for comprehensive staging and monitoring for familial syndromes.
- Aids clinicians in managing this rare pediatric malignancy effectively.
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