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Ketamine versus propofol for strabismus surgery in children
Ayse Mizrak1, Ibrahim Erbagci, Tulin Arici
1Anesthesiology and Reanimation, Gaziantep University School of Medicine, Gaziantep, Turkey.
Clinical Ophthalmology (Auckland, N.Z.)
|September 9, 2010
Summary
Ketamine infusion is more advantageous than propofol for pediatric strabismus surgery, showing lower anesthetic and antiemetic use, and reduced postoperative agitation. This study highlights ketamine
Area of Science:
- Pediatric Anesthesiology
- Ophthalmology
- Pharmacology
Background:
- Strabismus surgery in children requires careful anesthetic management.
- Both ketamine and propofol are used for pediatric anesthesia, each with potential benefits and drawbacks.
Purpose of the Study:
- To compare the efficacy and safety of intravenous ketamine versus propofol infusion for anesthesia in pediatric strabismus surgery.
Main Methods:
- A randomized study of 60 pediatric patients (aged 4-11 years) undergoing strabismus surgery.
- Patients received either ketamine (1-3 mg/kg/hr) or propofol (6-9 mg/kg/hr) infusion.
- Standard premedication with fentanyl and rocuronium bromide was administered prior to intubation.
Main Results:
- Ketamine group showed significantly lower consumption of anesthetics and antiemetics.
- Lower incidence of oculocardiac reflex observed in the ketamine group.
- Patients receiving ketamine experienced shorter recovery times, reduced postoperative agitation, and lower pain scores.
Conclusions:
- Intravenous ketamine infusion offers significant advantages over propofol for pediatric strabismus surgery.
- Ketamine anesthesia is associated with improved postoperative outcomes, including less agitation and pain.
- Ketamine is a favorable anesthetic choice for this pediatric surgical population.
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