Related Experiment Video
Updated: Jun 8, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
Published on: March 14, 2013
Thermoregulation in very low-birth-weight infants during the golden hour: results and implications
Robin L Bissinger1, David J Annibale
1College of Nursing, Medical University of South Carolina, USA. bissinrl@musc.edu
Insights
Maintaining normal body temperature is crucial for the survival of very low-birth-weight (VLBW) infants. Early interventions in the delivery room can significantly improve outcomes for these vulnerable newborns.
Area of Science:
- Neonatalogy
- Perinatal Medicine
- Pediatric Critical Care
Background:
- Very low-birth-weight (VLBW) infants face high morbidity and mortality rates due to innate vulnerability and environmental risks.
- Premature infants are susceptible to cold stress, especially in the initial hours and weeks of life, due to underdeveloped epidermal protective layers.
- Core body temperature rapidly declines post-birth in VLBW infants, increasing risks.
Purpose of the Study:
- To review evidence on thermoregulation in VLBW infants at birth.
- To highlight the critical importance of maintaining normal body temperature in the delivery room.
- To explore delivery room management strategies and early interventions for improved long-term outcomes.
Main Methods:
- Review of existing evidence on thermoregulation in VLBW infants.
- Analysis of factors affecting temperature control in the delivery room, during stabilization, and NICU admission.
- Examination of transepidermal water loss and temperature regulation strategies.
Main Results:
- Thermoregulation is a significant factor affecting VLBW infant survival.
- Hypothermia is a major contributor to morbidity and mortality in neonates.
- Effective delivery room management and early interventions are vital for improving outcomes.
Conclusions:
- Maintaining normothermia in the delivery room is critical for VLBW infant survival.
- Focusing on the "golden hour" of care with appropriate interventions can enhance adaptation and long-term outcomes.
- Proactive temperature management strategies are essential for this vulnerable population.
Abstract:
The survival of very low-birth-weight (VLBW) infants has been shown to be effected by alterations in thermoregulation. Morbidity and mortality in these VLBW infants has remained higher than those in any other group of infants because of their innate vulnerability and because of exposure to risk factors in the environment. This leaves the premature infant vulnerable to cold stress especially in the first hours to weeks of life. At birth, the VLBW infant emerges from a warm, fluid environment and is thrust into a cold, abrasive environment before the protective layers of the epidermis have developed. Within minutes of birth, the core temperature begins to fall, particularly in infants whose birth weights are less than 1500 g. Hypothermia is a major cause of morbidity and mortality in infants; therefore, maintaining normal body temperatures in the delivery room is crucial. We reviewed evidence related to thermoregulation at birth in VLBW infants, including transepidermal water loss and temperature control in the delivery room, during stabilization and upon admission to the neonatal intensive care unit. Delivery room management that focuses on the adaptation of the infant as well as early interventions that improve long-term outcomes may emphasize the "golden hour" of care and improve outcomes in this extremely vulnerable population.
Related Concept Videos
Decreased Body Temperature
Temperature Measurement Sites
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...
Thermoregulation
Factors Affecting Body Temperature
Factors may include:
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Homeostatic Imbalances in Body Temperature

