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Related Experiment Video

Updated: Jun 8, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Next-generation imaging development for nanoparticle biodistribution measurements.

Pushpa Tandon¹, Robert J Nordstrom

¹National Cancer Institute, National Institutes of Health, Cancer Imaging Program, Bethesda, MD 20892, USA. tandonp@mail.nih.gov

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology

|September 16, 2010

Summary

Quantitative imaging is crucial for understanding nanoparticle biodistribution in humans. Multidisciplinary networks are advancing imaging technologies and validation methods for nanomedicine applications.

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Last Updated: Jun 8, 2026

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Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Area of Science:

Biomedical Engineering
Nanotechnology
Medical Imaging

Background:

Nanotechnology's advancement necessitates precise in vivo biodistribution assessment.
Quantitative imaging methods are essential for tracking nanoconstructs and carriers within the body.
Simultaneous progress in imaging and nanotechnology requires integrated, multidisciplinary research efforts.

Purpose of the Study:

To highlight the critical role of quantitative imaging in nanomedicine.
To showcase the Network for Translational Research (NTR) as a model for collaborative imaging and probe development.
To emphasize the need for validated imaging techniques for in vivo nanoparticle studies.

Main Methods:

Development and optimization of multimodal imaging hardware and software.
Creation and testing of novel imaging probes for nanoconstructs.
Establishment of validation frameworks for imaging systems and agents.

Main Results:

NTR comprises four centers focused on advancing multimodal imaging and probe development.
The network addresses challenges in imaging technology, software, and probe design.
Efforts are aligned with the requirements for future in vivo nanoparticle biodistribution studies.

Conclusions:

Multidisciplinary networks are vital for accelerating nanomedicine research.
The NTR model facilitates resource sharing and consensus-building for imaging challenges.
Validation of imaging hardware and agents is paramount for successful nanomedicine translation.