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[Studies on the chemical constituents of Kalimeris indica]
Gang Wang1, Guo-Kai Wang, Jin-Song Liu
1School of Materia Madica, Anhui University of Traditional Chinese Medicine, Anhui Key Laboratory of Modernized Chinese Material Medical, Hefei 230031, China. kunhong_8@163.com
Objective:
To study the chemical constituents from Kalimeris indica.
Methods:
Compounds were isolated and purified with silica gel and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic analysis including MS and NMR.
Results:
Nine compounds were isolated and identified as tritriacontane (I), hexadecanol (II), chrysophanol (III), vanillin (IV), physcion (V), beta-sitosterol (VI), stigmasterol (VII), leinoleic acid (VII), emodin (IX).
Conclusion:
All of them, except compound IV, VI, are isolated from this genus for the first time. Compound III, IV had the protective effects with the toxicity of CCl4 on primary cultered hepatocytes.
