Related Experiment Video
Updated: Jun 8, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Early localized morphea mimicking an acquired port-wine stain
Rajiv I Nijhawan1, Susan Bard, Marianna Blyumin
1Department of Dermatology and Cutaneous Surgery, University of Miami-Miller School of Medicine, Miami, Florida 33125, USA.
Abstract:
Port-wine stains (PWS) and morphea are distinct conditions that are easily recognized and diagnosed in pediatric patients. Rarely, early localized morphea may mimic an acquired PWS. We present 4 such cases, in two of which the initial clinical impression of acquired PWS was thought to be confirmed by histopathology. A diagnosis of morphea was made approximately 6 months to 3 years after the onset of the acquired PWS. Clinicians should be aware that an apparent acquired PWS may be an early manifestation of localized morphea and continue to monitor these lesions.
Insights
Early localized morphea can mimic port-wine stains (PWS) in children. This mimicry can delay morphea diagnosis, even with initial histopathology confirmation of PWS. Continued monitoring is crucial for these pediatric lesions.
Area of Science:
- Pediatric Dermatology
- Dermatopathology
Background:
- Port-wine stains (PWS) and morphea are distinct pediatric skin conditions.
- Early localized morphea can present atypically, mimicking acquired PWS.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Endocarditis II: Clinical Features of Infective Endocarditis
Simple Staining Technique
