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Correction of atrophic scars with artefill: an open-label pilot study
Rachel E Epstein1, James M Spencer
1Nova Southeastern University/Largo Medical Center Dermatology Residency Program, Largo, FL, USA.
Background:
Artefill, a novel permanent filler approved by the U.S. Food and Drug Administration (FDA), has been used as an injectable implant for the correction of nasolabial folds. Fillers are considered a first line treatment for atrophic scars.
Objective:
The authors evaluated the degree of correction and subject satisfaction of correction of atrophic acne scar(s) after injection of Artefill.
Methods:
Fourteen qualified subjects participated in a single-center, open-label, pilot study. Atrophic acne scars were evaluated prior to injection. Subscision was performed, and then Artefill was injected into the scar. The degree of improvement was measured at weeks 2 and 4 and month 8. Subjects were asked to fill out a satisfaction survey at their eight-month visit.
Results:
Investigator ratings after eight months post procedure indicated that 96 percent of the atrophic acne scars showed some degree of improvement. There was no improvement in two out of a total of 57 scars evaluated. The majority of patients reported a moderate correction, correlating with a 51-75 percent improvement in their acne scars at eight months. No adverse events or side effects were noted.
Conclusion:
Artefill demonstrated to be both an efficacious and safe therapy for the treatment of atrophic acne scars.
