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Measles vaccination does not prevent multiple sclerosis.

S Bansil1, R Troiano, P C Dowling

  • 1Department of Neurology, University Hospital, Newark, N.J.

Neuroepidemiology
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

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Measles vaccination in childhood did not appear to prevent multiple sclerosis (MS) in a study of young patients. This suggests measles virus infection alone may not cause MS, and vaccination might not prevent it.

Area of Science:

  • Neurology
  • Immunology
  • Virology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease.
  • The potential link between measles virus infection and MS is under investigation.
  • Measles vaccination is known to prevent other neurological complications like SSPE.

Purpose of the Study:

  • To investigate the history of measles vaccination in young patients diagnosed with multiple sclerosis.
  • To explore the relationship between prior measles exposure and the development of MS.

Main Methods:

  • Retrospective study of 27 young patients with MS.
  • Review of immunization records for measles vaccination history.
  • Patient history collection for reported measles vaccination.

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Main Results:

  • Of 14 patients with available records, all received childhood measles vaccination.
  • An additional 8 patients reported a history of measles vaccination.
  • A significant proportion of young MS patients had received the measles vaccine.

Conclusions:

  • Measles virus infection is unlikely to be the sole cause of multiple sclerosis.
  • Unlike SSPE and post-measles encephalitis, MS may not be preventable through timely measles vaccination.