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Early pathomorphological changes and intracranial volume-pressure: relations following the experimental sagittal
K Tychmanowicz1, Z Czernicki, M Czosnyka
1Department of Neurosurgery, Medical Research Centre, Polish Academy of Sciences, Warsaw.
Acta Neurochirurgica. Supplementum
|January 1, 1990
Abstract:
Saggital sinus occlusion was produced in cats. The intracranial volume-pressure relations were studied using the lumbar infusion tests. Right after occlusion ICP rised from 7.1 +/- 1.8 to 12.4 +/- 4.1 mmHg. The values of outflow resistance and volume-pressure response increased also and remained significantly unchanged with only slight decrease of the volume-pressure response. The morphometric study of the surface veins showed the dilatation of the veins draining to the occluded saggital sinus for about 10-20%. No signs of the blood-brain barrier disruption were observed.