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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Patch-testing with plastics and glues series allergens.

Eugenia Shmidt1, Sara A Farmer, Mark D P Davis

  • 1Department of Dermatology and the Division of Biomedical Informatics and Biostatistics, Mayo Clinic, Rochester, MN, USA.

Dermatitis : Contact, Atopic, Occupational, Drug
|October 6, 2010
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Summary
This summary is machine-generated.

Patch testing for plastics and glues allergy is crucial. A specialized series identified significantly more allergies than a baseline series alone, aiding diagnosis in patients with suspected sensitivities.

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Area of Science:

  • Dermatology
  • Allergology
  • Contact Dermatitis

Background:

  • Limited US-based research exists on patch testing for plastics and glues.
  • Identifying allergens in plastics and glues is essential for diagnosing contact dermatitis.

Purpose of the Study:

  • To present patch testing results from a single institution for patients with suspected plastics and glues allergy.
  • To compare findings with existing published data on plastics and glues allergens.

Main Methods:

  • A retrospective review of 444 patients patch tested between 2000-2007.
  • Utilized a comprehensive plastics and glues series (up to 56 allergens) and a baseline series (up to 5 allergens).
  • Compared positive reaction rates with prior patch testing literature.

Main Results:

  • 22% of patients experienced irritant reactions, while 45% had allergic reactions.
  • Highest allergy rates were observed for bis(2-dimethylaminoethyl) ether, benzoyl peroxide, epoxy resin, bisphenol F, 2-hydroxyethyl methacrylate, and 2-hydroxyethyl acrylate.
  • The specialized series identified 193 patients with plastics and glues allergy, with 162 cases missed by the baseline series alone.

Conclusions:

  • Patch testing with a specialized series of plastics and glues allergens is vital for diagnosing suspected allergies.
  • Specialized series testing significantly enhances diagnostic yield compared to baseline series alone.