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Bowenoid papulosis turning to squamous cell carcinoma
1From the Department of Dermato-Venereology and Pathology Medical College Velappaya, Trichur-680596, India, .
Indian Journal of Dermatology, Venereology and Leprology
|October 6, 2010
Summary
Bowenoid papulosis, a genital lesion mimicking cancer-in-situ, can progress to invasive squamous cell carcinoma. This case highlights the malignant potential of scrotal Bowenoid papulosis in an elderly male.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Bowenoid papulosis presents as benign-appearing genital lesions.
- Histologically, it exhibits features of squamous cell carcinoma-in-situ.
- Malignant transformation to invasive squamous cell carcinoma is a known, albeit rare, complication.
Purpose of the Study:
- To report a case of scrotal Bowenoid papulosis progressing to invasive squamous cell carcinoma.
- To emphasize the importance of vigilant monitoring and early intervention for genital squamous lesions.
Main Methods:
- Clinical presentation and dermatoscopic examination.
- Histopathological analysis of the scrotal lesion.
- Review of relevant literature on Bowenoid papulosis and its malignant transformation.
Main Results:
- The patient, an elderly male, presented with a scrotal lesion initially diagnosed as Bowenoid papulosis.
- Histopathology confirmed progression to invasive squamous cell carcinoma.
- The case underscores the potential for aggressive behavior in scrotal Bowenoid papulosis.
Conclusions:
- Scrotal Bowenoid papulosis can transform into invasive squamous cell carcinoma.
- Early detection and appropriate management are crucial for preventing advanced disease.
- This case highlights the need for heightened awareness among clinicians regarding the malignant potential of genital squamous lesions.
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